منابع مشابه
Developmental neurobiology and the natural history of nerve growth factor.
I was invited to write about the discovery of Nerve Growth Factor and its relationship to developmental neurobiology. Rather than detail the life of NGF over the past 30 years, I wish to concentrate on what was the most attractive and also the most unusual feature in the investigation of NGF: that each finding has signaled a new turning point and opened up a new perspective. The story of NGF is...
متن کاملNerve Growth Factors and Neurotrophins
Cell division, cell death, and cell differentiation are hallmarks of embryogenesis. Such processes are supported by neurotrophins that have the capacity of regulating not only developmental processes, but also neuronal survival, morphological adaptation, and neural plasticity. Nerve growth factor (NGF) is a prototype of neurotrophins capable of influencing survival and differentiation of neuron...
متن کاملRita Levi-Montalcini: the discovery of nerve growth factor and modern neurobiology.
The remarkable accomplishments in developmental neurobiology within the past 60 years have depended on two things: (i) a succession of original histochemical and immunohistochemical methodologies for identifying pathways in the nervous system with increasing precision and sensitivity, and (ii) the discovery of growth factors for neurons. Growth factors are naturally occurring, essential biologi...
متن کاملMitogenic growth factors and nerve dependence of limb regeneration.
Regeneration of the amphibian limb after amputation depends on division of blastemal cells, the progenitor cells of the regenerate. This division is controlled, at least in the early stages of regeneration, by the nerve supply to the blastema. A monoclonal antibody to newt blastema cells has provided evidence that Schwann cells and muscle fibers contribute to the blastema, and identifies blaste...
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JULY/AUGUST 2003 31 Nobel Prize winners disagree about the impact of the financial sector on economic growth. Some do not even consider finance worth discussing. A collection of essays by the “pioneers of development economics”—including three winners of the Nobel Prize in Economics—does not discuss finance (Meier and Seers, 1984). At the other extreme, Nobel Prize winner Merton Miller (1998, p...
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ژورنال
عنوان ژورنال: Nature
سال: 1984
ISSN: 0028-0836,1476-4687
DOI: 10.1038/307500a0